事業推進担当者: Richard A Cohen (リチャード エー コーエン)

事業推進担当者 | 特別研究教員 | RA・特別研究員

Richard A Cohen (リチャード エー コーエン)

Jay and Louise Coffman Professor of Vascular Medicine, Boston University School of Medicine

主な研究業績

1. Adachi T, Weisbrod RM, Pimentel D, Ying J, Sharov VS, Schoneich C, Cohen RA. S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide. A mechanism targeted by oxidants in vascular disease. Nat Med. 2004 Nov;10(11):1200-7.
2. Sethuraman M, McComb ME, Huang W, Huang S, Heibeck T, Costello CE, Cohen RA. Isotope-coded affinity tag (ICAT) approach to redox proteomics: Identification and quantitation of oxidant-sensitive cysteine thiols in complex protein mixtures. J Proteome Res. 2004 Nov-Dec;3(6):1228-33.
3. Zang M, Xu S, Maitland-Toolan KA, Zuccollo A, Hou X, Jiang B, Wierzbicki M, Verbeuren TJ, Cohen RA. Polyphenols Stimulate AMP-Activated Protein Kinase, Lower Lipids, and Inhibit Accelerated Atherosclerosis in Diabetic LDL Receptor-Deficient Mice. Diabetes. 2006 Aug;55(8):2180-91.
4. Xu S, Ying J, Jiang B, Guo W, Adachi T, Sharov V, Lazar H, Menzoian J, Knyushko TV, Bigelow D, Sch?neich C, Cohen RA. Detection of Sequence-Specific Tyrosine Nitration of Manganese SOD and SERCA in Cardiovascular Disease and Aging. Am J Physiol Heart Circ Physiol. 2006 Jun;290(6):H2220-7.
5. Ying J, Tong XY, Pimental DR, Weisbrod RM, Trucillo MP, Adachi T, Cohen RA. Cysteine-674 of the sarco/endoplasmic reticulum calcium ATPase is required for the inhibition of cell migration by nitric oxide. Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):783-90.

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