Cluster for Cell Cycle, differentiation and metabolism

Scope

The scope of the cell cycle, differentiation and metabolism cluster includes investigation of the role cellular energetics and metabolic remodeling play in cellular locomotion, proliferation and differentiation.

Overview

  • Investigating the mechanisms of the development of the functional cellular community in the cerebral cortex. (Prof. Nakajima)
  • Understanding the mechanisms that regulate neurogenesis and neuronal regeneration in the adult brain. (Prof. Sawamoto)
  • Understanding the molecular mechanisms that regulate salt and water transport and maintain brain water homeostasis. Important molecules and membrane proteins include: dopamine, Na, K-ATPase and aquaporin. (Prof. Aperia)
  • Elucidating the regulatory system and homeostasis of bone metabolism. (Prof. Miyamoto)

News

People

Core members

Kazunori Nakajima Kazunobu Sawamoto Anita Aperia Takeshi Miyamoto

Kazunori Nakajima

Professor and chair
Department of Anatomy, Keio University School of Medicine, Tokyo, Japan

Kazunobu Sawamoto

Professor
Department of Developmental and Regenerative Biology
Institute of Molecular Medicine
Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan

Anita Aperia

Professor
Department of Woman and Child Health
Research Lab, Q2:09
Astrid Lindgren Children's Hospital
Karolinska University Hospital
171 76 Stockholm, Sweden

Takeshi Miyamoto

Associate professor
Department of Orthopedic Surgery, Keio university School of Medicine, Tokyo, Japan

Jeffrey Golden

Jeffrey Golden

Professor
Part-time Lecturer/Pathologist-in-Chief/Professor
Department of Anatomy/Children's Hospital of Philadelphia/Pathology & Laboratory Medicine Univ. of Pennsylvania School of Medicine, Pennsylvania, USA

Faculty, fellow and RA

Takeshi Kawauchi

Assistant Professor

Department of Anatomy, Keio University School of Medicine, Tokyo, Japan

Norihito Kishimoto

Instructor

Center for Integrated Medical Research, Nagoya City University, Nagoya, Japan

Shigeaki Kanatani

Instructor

Department of Anatomy, Keio University School of Medicine, Tokyo, Japan

Daisuke Tanaka

Instructor

Department of Anatomy, Keio University School of Medicine, Tokyo, Japan

Yoshiteru Miyamoto

Instructor

Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan

Hiroko Hoshi

Instructor

Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan

Shigeyuki Yoshida

RA

Department of Dentistry and Oral Surgery, School of Medicine, Keio University, Tokyo, Japan

Yukiko Sasazawa

RA

School of Fundamental Science and Technology, Graduate School of Science and Technology, Keio University, Tokyo, Japan

Kota Yamamoto

RA

School of Fundamental Science and Technology, Graduate School of Science and Technology, Keio University, Tokyo,

Satoko Shinjo

RA

School of Fundamental Science and Technology, Graduate School of Science and Technology, Keio University, Tokyo,

Yasuyo Wada

RA

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University, School of. Medicine, Tokyo, Japan

Toshihiro Nomura

RA

Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan

Bao Yan

RA

Department of Biochemistry & Integrative Medical Biology, School of Medicine, Keio University, Tokyo, Japan

Sayaka Kusuzawa

RA

Department of Anatomy, Keio University School of Medicine, Tokyo, Japan

Katsutoshi Sekine

RA

Department of Anatomy, Keio University School of Medicine, Tokyo, Japan

Hiroya Miyamoto

RA

Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan

Osama Mohamed Aly Ibrahim

RA

Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan

Hiroki Kobayashi

RA

School of Fundamental Science and Technology, Graduate School of Science and Technology, Keio University, Tokyo,

Kenji Tomita

RA

Department of Anatomy, Keio University School of Medicine, Tokyo, Japan

Haruki Toriumi

RA

Department of Neurology, Keio University School of Medicine, Tokyo, Japan

Yoko Osumi

RA

Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan

Pictures

Neurons in the neocortex are arranged in a highly coordinated manner. IN this image, they are labeled in utero by electroporation (Green) and using two birth-date markers (Blue and Magenta).

The Image shows that the transcription factor COUP-TFII is preferentially expressed in the caudal part of the telencephalon and is involved in the migration of GABAergic interneurons (Kanatani et al., J. Neurosci., 2008).

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